NKX2 Monoclonal Antibody (OTI1C5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA810448

Catalog No. 50-168-3395

Description

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NKX2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P43699
• Gene Symbols: NKX2-1
• Immunogen: Full length human recombit protein of human NKX2-1 ( NP_003308) produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: OTI1C5
• Conjugate: Unconjugated
• Gene: NKX2-1
• Gene Alias: BCH, BHC, NK-2, NKX2.1, NKX2A, NMTC1, T/EBP, TEBP, TITF1, TTF-1, TTF1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7080
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid