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Invitrogen™ Nkx6.1 Polyclonal Antibody
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Catalog No. PIPA5103899
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100 μL
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PIPA5103899 100 μL
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Catalog No. PIPA5103899 Supplier Invitrogen™ Supplier No. PA5103899
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NKX61.

NKX6.1 is a bi-functional transcription factor that has effects in both the central nervous system and in the pancreas. It has both expression and repression effects on genes, leading to the proper formation of motoneurons, oligodendrocytes, and insulin-secreting beta cells. It is known to interact with Pax6 and Pdx-1, probably at or near the 60 amino acid homeobox DNA-binding domain. Due to its obvious relationship to beta cells and CNS, NKX6.1 is becoming a more interesting target for therapies in diabetes and certain brain diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nkx6.1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NKX6-1
Gene Accession No. O35762, P78426, Q99MA9
Gene Alias Drosophila NK transcription factor related, gene family 6, locus 1; homeobox protein NK-6 homolog A; Homeobox protein Nkx-6.1; homeodomain transcription factor Nkx6.1; NK homeo box, family 6, member A; NK homeobox, family 6, A; NK6 homeobox 1; NK6 transcription factor homolog A; NK6 transcription factor related locus 1; NK6 transcription factor related, locus 1; Nkx6.1; Nkx61; NKX6-1; Nkx6a
Gene Symbols NKX6-1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NKX6-1(Accession P78426), corresponding to amino acid residues M209-K259.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18096, 4825, 65193
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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