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Invitrogen™ Nkx6.1 Polyclonal Antibody
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Catalog No. PIPA523070
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100 μL
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PIPA523070 100 μL
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Catalog No. PIPA523070 Supplier Invitrogen™ Supplier No. PA523070
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Description

Rabbit Polyclonal Antibody

Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

NKX6.1 is a bi-functional transcription factor that has effects in both the central nervous system and in the pancreas. It has both expression and repression effects on genes, leading to the proper formation of motoneurons, oligodendrocytes, and insulin-secreting beta cells. It is known to interact with Pax6 and Pdx-1, probably at or near the 60 amino acid homeobox DNA-binding domain. Due to its obvious relationship to beta cells and CNS, NKX6.1 is becoming a more interesting target for therapies in diabetes and certain brain diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nkx6.1
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.05% sodium azide
Gene NKX6-1
Gene Accession No. O35762, P78426, Q99MA9
Gene Alias Drosophila NK transcription factor related, gene family 6, locus 1; homeobox protein NK-6 homolog A; Homeobox protein Nkx-6.1; homeodomain transcription factor Nkx6.1; NK homeo box, family 6, member A; NK homeobox, family 6, A; NK6 homeobox 1; NK6 transcription factor homolog A; NK6 transcription factor related locus 1; NK6 transcription factor related, locus 1; Nkx6.1; Nkx61; NKX6-1; Nkx6a
Gene Symbols NKX6-1
Host Species Rabbit
Immunogen A genomic peptide made to an internal region of the human Nkx6.1 protein (within residues 50-200).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18096, 4825, 65193
Target Species Human, Mouse, Rat, Zebrafish
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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