Invitrogen™ NLGN3 Monoclonal Antibody (N110/29), APC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545697

Catalog No. PIMA545697

Description

Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2. 1 μg/mL of MA5-45697 was sufficient for detection of Neuroligin 3 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 110kDa. Does not cross-react with Neuroligin-1, -2, -4 or -4. This antibody was formerly sold as clone S110-29.

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Specifications

• Antigen: NLGN3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
• Gene Accession No.: Q62889, Q8BYM5, Q9NZ94
• Gene Symbols: NLGN3
• Immunogen: Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: N110/29
• Conjugate: APC
• Gene: NLGN3
• Gene Alias: A230085M13Rik; ASPGX1; AUTSX1; Gliotactin homolog; HNL3; KIAA1480; neuroligin 3; neuroligin 3 protein; neuroligin-3; NL3; NLGN3
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 171297, 245537, 54413
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

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