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Invitrogen™ NLGN4X Monoclonal Antibody (N98/7)
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Catalog No. PIMA527585
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100 μg
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Catalog No. Quantity
PIMA527585 100 μg
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Catalog No. PIMA527585 Supplier Invitrogen™ Supplier No. MA527585
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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-27585 was sufficient for detection of Neuroligin 4 in 20 μg of mouse brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 125-130kDa. Does not cross-react with other Neuroligins. This antibody was formerly sold as clone S98-7.

Neuroligin-4, X linked (also known as NLGN4X, NLGN4, Neuroligin-4, and Neuroligin 4X) is a postsynaptic cell-adhesion molecule that interacts with presynaptic cell-surface neurexins. These interactions bridge together the synaptic cleft and have an essential role in synaptic transmissions between neurons. There are 5 neuroligin genes in humans: NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN4Y. Mutations in NLGN3 and NLGN4X are linked to Autism Spectrum Disorders (ASD). The expression of neuroligin-4, X-linked has been reported on human pluripotent stem cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NLGN4X
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone N98/7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
Gene Nlgn4l
Gene Accession No. B0F2B4
Gene Alias ASPGX2; AUTSX2; HLNX; HNL4X; HNLX; KIAA1260; MGC22376; neuroligin 4, X-linked; neuroligin 4-like; Neuroligin X; Neuroligin-4, X-linked; NL4; NL-4; NLGN; Nlgn4; Nlgn4l; NLGN4X; UNQ365/PRO701
Gene Symbols Nlgn4l
Host Species Mouse
Immunogen Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin 4. ~45% identity with Neuroligin-1, -2 and -3.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100113365
Target Species Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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