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Invitrogen™ NLRC4 Polyclonal Antibody
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Catalog No. PA14264
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100 μg
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Catalog No. Quantity
PA14264 100 μg
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Catalog No. PA14264 Supplier Invitrogen™ Supplier No. PA14264
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Description

Rabbit Polyclonal Antibody

PA1-4264 detects CLAN protein from human samples. This antibody detects both A and B isoforms. PA1-4264 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~116 kDa protein representing CLAN-A and a ~43 kDa protein representing CLAN-B in lung lysate. PA1-4264 immunizing peptide corresponds to N-terminal sequence M N F I K D N S R A L I Q R M G M.

NLRC4 encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NLRC4
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Nlrc4
Gene Accession No. Q9NPP4
Gene Alias 9530011P19Rik; AIFEC; CARD, LRR, and NACHT-containing protein; Card12; caspase recruitment domain family, member 12; caspase recruitment domain-containing protein 12; CLAN; Clan protein; CLAN1; CLANA; CLANB; CLANC; CLAND; CLR2.1; FCAS4; ice protease-activating factor; ICE-protease activating factor; ipaf; NLR family CARD domain containing 4; NLR family CARD domain-containing protein 4; NLR family, CARD domain containing 4; NLRC4; NOD-like receptor C4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4; UNQ6189/PRO20215
Gene Symbols Nlrc4
Host Species Rabbit
Immunogen Synthetic Peptide corresponding to the N-terminal sequence M N F I K D N S R A L I Q R M G M.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58484
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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