Invitrogen™ NLRP4G Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579741

Catalog No. PIPA579741

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Mouse Ovary Tissue. IHC: human lung cancer tissue.

The protein encoded by this gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). This gene product has a demonstrated role as a negative regulator of autophagy and type I interferon signaling pathways as a result of protein interactions with its NACHT domain. The PYD domain has also been shown to be important in the inhibition of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells).

Specifications

• Antigen: NLRP4G
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nlrp4g
• Gene Alias: nalp4g; NLR family, pyrin domain containing 4G; Nlrp4g
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 235779
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: 0
• Gene Symbols: Nlrp4g
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse NLRP4G (704-721aa SLQYLDLGCSFLTHSEVK).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG