Invitrogen™ NMBR Monoclonal Antibody (466505)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524187

Catalog No. PIMA524187

Description

This antibody stains human Neuromedin B R/NMBR transfectants but not irrelevant transfectants. Reconstitute at 0.5 mg/mL in sterile PBS.

NMBR, also known as neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.

Specifications

• Antigen: NMBR
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P28336
• Gene Symbols: NMBR
• Immunogen: NS0 mouse myeloma cell line transfected with human NMBR Met1-Met390.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry
• Clone: 466505
• Conjugate: Unconjugated
• Gene: NMBR
• Gene Alias: BB1; BB182387; BB1R; bombesin receptor 1; epididymis secretory sperm binding protein Li 185a; epididymis tissue protein Li 185a; neuromedin B receptor; neuromedin-B receptor; Neuromedin-B-preferring bombesin receptor; NMBR; NMB-R
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 4829
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized