Invitrogen™ NMBR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102109

Catalog No. PIPA5102109

Description

Antibody detects endogenous levels of total NMBR.

NMBR, also known as neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.

Specifications

• Antigen: NMBR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NMBR
• Gene Alias: BB1; BB182387; BB1R; bombesin receptor 1; epididymis secretory sperm binding protein Li 185a; epididymis tissue protein Li 185a; neuromedin B receptor; neuromedin-B receptor; Neuromedin-B-preferring bombesin receptor; NMBR; NMB-R
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18101, 25264, 4829
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O54799, P24053, P28336
• Gene Symbols: NMBR
• Immunogen: A synthesized peptide derived from human NMBR(Accession P28336), corresponding to amino acid residues S229-W279.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov