Invitrogen™ NMBR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533970

Catalog No. PIPA533970

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Panda, Bovine, Bat, Horse, Rabbit, Pig (100%).

NMBR, also known as neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.

Specifications

• Antigen: NMBR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NMBR
• Gene Alias: BB1; BB182387; BB1R; bombesin receptor 1; epididymis secretory sperm binding protein Li 185a; epididymis tissue protein Li 185a; neuromedin B receptor; neuromedin-B receptor; Neuromedin-B-preferring bombesin receptor; NMBR; NMB-R
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100060776, 100169653, 100351510, 18101, 4829, 539776
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: O54799, P28336
• Gene Symbols: NMBR
• Immunogen: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human NMBR.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rabbit, Bovine, Pig, Horse, Bat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov