Invitrogen™ NMD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100291

Catalog No. PIPA5100291

Description

Antibody detects endogenous levels of total NMD3.

NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.

Specifications

• Antigen: NMD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nmd3
• Gene Alias: 60S ribosomal export protein NMD3; C87860; CGI-07; hNMD3; Nmd3; NMD3 homolog; NMD3 homolog (S. cerevisiae); NMD3 ribosome export adaptor; RGD1308468
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 310512, 51068, 97112
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q96D46, Q99L48
• Gene Symbols: Nmd3
• Immunogen: A synthesized peptide derived from human NMD3(Accession Q96D46), corresponding to amino acid residues L385-D435.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov