Invitrogen™ NMD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578616

Catalog No. PIPA578616

Description

Positive Control: mouse heart Predicted Reactivity: Human (100%), Zebrafish (82%), Bovine (96%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.

Specifications

• Antigen: NMD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nmd3
• Gene Alias: 60S ribosomal export protein NMD3; C87860; CGI-07; hNMD3; Nmd3; NMD3 homolog; NMD3 homolog (S. cerevisiae); NMD3 ribosome export adaptor; RGD1308468
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 310512, 51068, 97112
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.65 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q96D46, Q99L48
• Gene Symbols: Nmd3
• Immunogen: Recombinant protein encompassing a sequence within the center region of human NMD3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG