NMDAR1 (extracellular) Polyclonal Antibody, Invitrogen™

Guinea Pig Polyclonal Antibody

Supplier:  Thermo Scientific PA5111814

Catalog No. PIPA5111814

Description

Reconstitute antibody with 50 μL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Peptide sequence is: ETEKPRGYQM STRLK(C) Homology: Human, mouse amino acid residues identical

NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Specifications

• Antigen: NMDAR1 (extracellular)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRIN1
• Gene Alias: GluN1; GluRdelta1; Glurz1; GluRzeta1; Glutamate [NMDA] receptor subunit zeta-1; Glutamate receptor ionotropic, NMDA 1; Grin1; M100174; MRD8; NMDA receptor 1; NMDA1; Nmdar; NMDAR1; NMD-R1; NMDZ1; N-methyl-D-aspartate receptor 1; N-methyl-D-aspartate receptor subunit NR1; NMZ1; NR1; NR1C1; NR1C2; NR1C2′; NR1N1; pGluN1; Rgsc174; RP11-350O14.1
• Host Species: Guinea Pig
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14810, 24408, 2902
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P35438, P35439, Q05586
• Gene Symbols: GRIN1
• Immunogen: Peptide corresponding to amino acid residues 385-399 of rat GluN1 (Extracellular, N-terminus)
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG