Invitrogen™ NMDAR2A Monoclonal Antibody (N327/95), PE

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545603

Catalog No. PIMA545603

Description

1 μg/mL of MA5-45603 was sufficient for detection o GluN2A/NR2A in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 170kDa. Does not react with NR2B. This antibody was formerly sold as clone S327-95.

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NMDAR2A
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
• Gene Accession No.: P35436, Q00959, Q12879
• Gene Symbols: Grin2a
• Immunogen: Fusion protein amino acids 75-325 (extracellular N-terminus) of rat GluN2A/NR2A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: N327/95
• Conjugate: PE
• Gene: Grin2a
• Gene Alias: EPND; FESD; GluN2A; GluRepsilon1; glutamate [NMDA] receptor subunit epsilon-1; glutamate ionotropic receptor NMDA type subunit 2A; glutamate receptor; glutamate receptor ionotropic, NMDA 2A; glutamate receptor, ionotropic, NMDA2A (epsilon 1); glutamate receptor, ionotropic, N-methyl D-aspartate 2A; Grin2a; hNR2A; LKS; NMDA Receptor 2A; NMDAR 2A; NMDAR2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subunit 2A; NR2A; OTTHUMP00000160135; OTTHUMP00000174531
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 14811, 24409, 2903
• Content And Storage: 4°C
• Form: Liquid