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Invitrogen™ NMDAR2D Polyclonal Antibody
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Catalog No. PIPA5101608
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PIPA5101608 100 μL
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Catalog No. PIPA5101608 Supplier Invitrogen™ Supplier No. PA5101608
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GRIN2D.

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors exhibit slow kinetsis of Ca2+ ions and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilon 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NMDAR2D
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GRIN2D
Gene Accession No. O15399, Q03391, Q62645
Gene Alias EB11; estrogen receptor binding CpG island; GluN2D; glur epsilon 4; GluRepsilon4; glutamate [NMDA] receptor subunit epsilon-4; glutamate ionotropic receptor NMDA type subunit 2D; glutamate receptor; glutamate receptor ionotropic, NMDA 2D; glutamate receptor, ionotropic, NMDA2D; glutamate receptor, ionotropic, NMDA2D (epsilon 4); glutamate receptor, ionotropic, N-methyl D-aspartate 2D; GRIN2D; ionotropic NMDA glutamate receptor epsilon 4 subunit type 2; NMDAR2D; N-methyl D-aspartate receptor subtype 2D; N-methyl-d-aspartate receptor subunit 2D; NR2D
Gene Symbols GRIN2D
Host Species Rabbit
Immunogen A synthesized peptide derived from human GRIN2D(Accession O15399), corresponding to amino acid residues Y673-R723.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14814, 24412, 2906
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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