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Invitrogen™ NMDAR3A/NMDAR3B Monoclonal Antibody (K35/40)
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Catalog No. PIMA126500
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50 μg
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Catalog No. Quantity
PIMA126500 50 μg
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Catalog No. PIMA126500 Supplier Invitrogen™ Supplier No. MA126500
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Description

Mouse Monoclonal Antibody

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Grin3a is an NMDA (N-methyl-D-aspartate) receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Grin3a is mediated by glycine and may play a role in the development of dendritic spines. Further, Grin3a may play a role in PPP2CB-NMDAR mediated signaling mechanism. Grin3a belongs to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. Grin3a shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in Grin3a suggest that the protein may be involved in the development of synaptic elements by modulating NMDA receptor activity. Diseases associated with GRIN3A include Lingual-Facial-Buccal Dyskinesia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NMDAR3A/NMDAR3B
Applications Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone K35/40
Concentration 1.4 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene GRIN3B
Gene Accession No. A2AIR5, O60391, Q8TCU5, Q8VHN2, Q91ZU9, Q9R1M7
Gene Alias 6430537F04; A830097C19Rik; chi-1; GluN3A; GluN3B; glutamate [NMDA] receptor subunit 3A; glutamate [NMDA] receptor subunit 3B; glutamate ionotropic receptor NMDA type subunit 3A; glutamate ionotropic receptor NMDA type subunit 3B; glutamate receptor; Glutamate receptor chi-1; Glutamate receptor ionotropic, NMDA 3A; glutamate receptor ionotropic, NMDA 3B; glutamate receptor ionotropic, NMDA3A; glutamate receptor, ionotropic, NMDA3B; glutamate receptor, ionotropic, N-methyl-D-aspartate 3A; glutamate receptor, ionotropic, N-methyl-D-aspartate 3B; GRIN3A; Grin3b; KIAA1973; mKIAA1973; NMDA receptor 4; NMDA receptor subunit 3B; NMDA type glutamate receptor subunit NR3B; NMDAR3A; NMDAR3B; NMDAR-L; NMDAR-L1; N-methyl-D-aspartate receptor; N-methyl-D-aspartate receptor subtype 3A; N-methyl-D-aspartate receptor subtype 3B; N-methyl-D-aspartate receptor subunit NR3B; NR3; NR3A; NR3B; Nr4
Gene Symbols GRIN3A, GRIN3B
Host Species Mouse
Immunogen Fusion protein, corresponding to amino acids 780-914 from the intracellular IIIIV loop of Human NMDAR3A + NMDAR3B.
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116443, 116444, 170483, 170796, 191573, 242443
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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