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Invitrogen™ NME3 Polyclonal Antibody

Catalog No. PIPA5121740
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200 μL
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PIPA5121740 20 μL
PIPA5119311 200 μL
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Catalog No. PIPA5121740 Supplier Invitrogen™ Supplier No. PA5121740
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Description

Rabbit Polyclonal Antibody

NME3 Polyclonal Antibody for Western Blot, IHC (P)

NME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NME3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene NME3
Gene Accession No. Q13232, Q9WV85
Gene Alias 1810009F08Rik; AI413736; c371H6.2; DR-nm23; expressed in non-metastatic cells 3; expressed in non-metastatic cells 3 protein (nucleoside diphosphate kinase); expressed in non-metastatic cells 3, protein (nucleoside diphosphate kinase); NDK 3; Ndk3; NDP kinase 3; NDP kinase C; NDPKC; NDPK-C; NM23-dr; NM23H3; nm23-H3; nm23-M3; NME/NM23 nucleoside diphosphate kinase 3; Nme3; non-metastatic cell expressed protein 3; non-metastatic cells 3, protein expressed in; nucleoside diphosphate kinase 3; Nucleoside diphosphate kinase C; nucleoside diphosphate kinase DR-nm23
Gene Symbols NME3
Host Species Rabbit
Immunogen Recombinant protein Non Metastatic Cells 3, Protein NM23A. The antigen corresponds to amino acid range 1-168 of the target protein.
Purification Method Antigen affinity chromatography, Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100514398, 4832, 79059
Target Species Human, Mouse, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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