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Invitrogen™ NME3 Polyclonal Antibody
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Catalog No. PIPA528793
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100 μL
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PIPA528793 100 μL
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Catalog No. PIPA528793 Supplier Invitrogen™ Supplier No. PA528793
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, H1299, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

NME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NME3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene NME3
Gene Accession No. Q13232
Gene Alias 1810009F08Rik; AI413736; c371H6.2; DR-nm23; expressed in non-metastatic cells 3; expressed in non-metastatic cells 3 protein (nucleoside diphosphate kinase); expressed in non-metastatic cells 3, protein (nucleoside diphosphate kinase); NDK 3; Ndk3; NDP kinase 3; NDP kinase C; NDPKC; NDPK-C; NM23-dr; NM23H3; nm23-H3; nm23-M3; NME/NM23 nucleoside diphosphate kinase 3; Nme3; non-metastatic cell expressed protein 3; non-metastatic cells 3, protein expressed in; nucleoside diphosphate kinase 3; Nucleoside diphosphate kinase C; nucleoside diphosphate kinase DR-nm23
Gene Symbols NME3
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human nm23-H3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4832
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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