Invitrogen™ NME4 Polyclonal Antibody

Catalog No.	Quantity
PIPA578081	100 μL

Catalog No. PIPA578081 Supplier Invitrogen™ Supplier No. PA578081

Description

Rabbit Polyclonal Antibody

Positive Control: human NME4-transfected 293T cells Predicted Reactivity: Xenopus laevis (80%), Pig (90%), Rhesus Monkey (99%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

NME4 is a protein kinases, which are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

Specifications

• Antigen: NME4
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene: NME4
• Gene Accession No.: O00746, Q9WV84
• Gene Alias: 2610027N22Rik; 2810024O08Rik; 5730493H09Rik; expressed in non-metastatic cells 4, protein; NDK; NDP kinase D; NDP kinase, mitochondrial; NDPKD; NDPK-D; NM23D; NM23H4; nm23-H4; Nm23M4; NM23-M4; NM23-Z4; NME/NM23 nucleoside diphosphate kinase 4; Nme4; non-metastatic cells 4, protein expressed in; nucleoside diphosphate kinase 4; nucleoside diphosphate kinase D; Nucleoside diphosphate kinase, mitochondrial; Unknown (protein for MGC:134183); zgc:56482
• Gene Symbols: NME4
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the center region of human NME4. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4833, 56520, 685679
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG