Invitrogen™ NME7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578647

Catalog No. PIPA578647

Description

Positive Control: human embryonic stem cell, human LUC shRNA-transfected human embryonic stem cells, human Nme7-1 shRNA-transfected human embryonic stem cells Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Specifications

• Antigen: NME7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NME7
• Gene Alias: CFAP67; cilia and flagella associated protein 67; D530024H21Rik; MN23H7; NDK 7; NDK7; NDP kinase 7; nm23-H7; Nm23-M7; Nm23-r7; NME/NM23 family member 7; Nme7; non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase); nucleoside diphosphate kinase 7; nucleoside diphosphate kinase 7-like protein; nucleoside-diphosphate kinase; nucleoside-diphosphate kinase 7; nucleoside-diphosphate kinase 7 isoform a
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171567, 29922
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.08 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9QXL8, Q9Y5B8
• Gene Symbols: NME7
• Immunogen: Mouse nm23-H7.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov