Invitrogen™ NMI Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527804

Catalog No. PIPA527804

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Raji. Predicted reactivity: Rhesus Monkey (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.

Specifications

• Antigen: NMI
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NMI
• Gene Alias: N-mcy (and STAT) interactor; Nmi; N-myc (and STAT) interactor; N-myc and STAT interactor; N-myc interactor; N-myc-interactor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9111
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.69 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q13287
• Gene Symbols: NMI
• Immunogen: Recombinant protein encompassing a sequence within the center region of human N-myc interactor. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG