Invitrogen™ NMI Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552584

Catalog No. PIPA552584

Description

Immunogen sequence: KINVTEIPDT LREDQMRDKL ELSFSKSRNG GGEVDRVDYD RQSGSAVITF VEIGVADKIL KKKEYPLYIN QTCHRVTVSP YTEIHLKKYQ IFSGTSKRTV LLTGMEGIQM DEEIVEDLIN IHFQRAKNGG GEVDVVKCSL GQPH Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 46%.

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.

Specifications

• Antigen: NMI
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NMI
• Gene Alias: N-mcy (and STAT) interactor; Nmi; N-myc (and STAT) interactor; N-myc and STAT interactor; N-myc interactor; N-myc-interactor
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9111
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13287
• Gene Symbols: NMI
• Immunogen: Recombinant protein corresponding to Human NMI. Recombinant protein control fragment (Product #RP-89342).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov