Invitrogen™ NMNAT1 Monoclonal Antibody (675112)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524304

Catalog No. PIMA524304

Description

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Specifications

• Antigen: NMNAT1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q9HAN9
• Gene Symbols: NMNAT1
• Immunogen: Sf 21-derived recombinant human NMNAT-1 Met1-Thr279.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Frozen)
• Clone: 675112
• Conjugate: Unconjugated
• Gene: NMNAT1
• Gene Alias: 2610529L11Rik; 5730441G13Rik; D4Cole1e; deamido-NAD(+) diphosphorylase; deamido-NAD(+) pyrophosphorylase; EC 2.7.7.1; EC 2.7.7.18; id:ibd5068; im:7144541; LCA9; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; naMN adenylyltransferase 1; nicotinamide mononucleotide adenylyl transferase; nicotinamide mononucleotide adenylyl transferase 1; nicotinamide mononucleotide adenylyltransferase 1; nicotinamide mononucleotide adenylyltransferase 1-like protein; nicotinamide nucleotide adenylyltransferase 1; nicotinamide/nicotinate mononucleotide adenylyltransferase 1; nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1; nicotinamide-nucleotide adenylyltransferase 1; Nicotinate-nucleotide adenylyltransferase 1; NMN adenylyltransferase 1; NMN/NaMN adenylyltransferase 1; nmnat; NMNAT1; NMNATPNAT1; PNAT1; PNAT-1; pyridine nucleotide adenylyltransferase 1; zgc:110243
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 64802
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized