Invitrogen™ NMNAT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543246

Catalog No. PIPA543246

Description

Peptide sequence: PVGDAYKKKG LIPAYHRVIM AELATKNSKW VEVDTWESLQ KEWKETLKVL Sequence homology: Cow: 93%; Dog: 93%; Goat: 79%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%.

The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Specifications

• Antigen: NMNAT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NMNAT1
• Gene Alias: 2610529L11Rik; 5730441G13Rik; D4Cole1e; deamido-NAD(+) diphosphorylase; deamido-NAD(+) pyrophosphorylase; EC 2.7.7.1; EC 2.7.7.18; id:ibd5068; im:7144541; LCA9; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; naMN adenylyltransferase 1; nicotinamide mononucleotide adenylyl transferase; nicotinamide mononucleotide adenylyl transferase 1; nicotinamide mononucleotide adenylyltransferase 1; nicotinamide mononucleotide adenylyltransferase 1-like protein; nicotinamide nucleotide adenylyltransferase 1; nicotinamide/nicotinate mononucleotide adenylyltransferase 1; nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1; nicotinamide-nucleotide adenylyltransferase 1; Nicotinate-nucleotide adenylyltransferase 1; NMN adenylyltransferase 1; NMN/NaMN adenylyltransferase 1; nmnat; NMNAT1; NMNATPNAT1; PNAT1; PNAT-1; pyridine nucleotide adenylyltransferase 1; zgc:110243
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 64802
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9HAN9
• Gene Symbols: NMNAT1
• Immunogen: Synthetic peptide directed towards the N-terminal of human NMNAT1 (aa 50-99).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov