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Invitrogen™ NMNAT3 Polyclonal Antibody
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Catalog No. PIPA563436
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100 μL
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PIPA563436 100 μL
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Catalog No. PIPA563436 Supplier Invitrogen™ Supplier No. PA563436
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VDPWESEQAQ WMETVKVLRH HHSKLLRSPP QMEGPDHGKA LFSTPAAVPE LKLLCGADVL KTFQTPNLWK DAHIQEIVEK FGLVCV Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 83%.

Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NMNAT3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NMNAT3
Gene Accession No. Q96T66
Gene Alias 4933408N02Rik; FKSG76; naMN adenylyltransferase 1; naMN adenylyltransferase 3; nicotinamide mononucleotide adenylyltransferase 3; nicotinamide nucleotide adenylyltransferase 3; Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3; nicotinamide-nucleotide adenylyltransferase 3; nicotinate-nucleotide adenylyltransferase 1; nicotinate-nucleotide adenylyltransferase 3; NMN adenylyltransferase 3; NMN/NaMN adenylyltransferase 3; NMNAT3; PNAT3; PNAT-3; pyridine nucleotide adenylyltransferase 3
Gene Symbols NMNAT3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NMNAT3. Recombinant protein control fragment (Product #RP-96415).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 349565
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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