NMNAT3 Polyclonal Antibody, Invitrogen™

Goat Polyclonal Antibody

Supplier:  Thermo Scientific PA5142781

Catalog No. PIPA5142781

Description

Additional Information: This antibody is expected to recognize both reported isoforms (NP_835471.1; NP_001186976.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury.

Specifications

• Antigen: NMNAT3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NMNAT3
• Gene Alias: 4933408N02Rik; FKSG76; naMN adenylyltransferase 1; naMN adenylyltransferase 3; nicotinamide mononucleotide adenylyltransferase 3; nicotinamide nucleotide adenylyltransferase 3; Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3; nicotinamide-nucleotide adenylyltransferase 3; nicotinate-nucleotide adenylyltransferase 1; nicotinate-nucleotide adenylyltransferase 3; NMN adenylyltransferase 3; NMN/NaMN adenylyltransferase 3; NMNAT3; PNAT3; PNAT-3; pyridine nucleotide adenylyltransferase 3
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 74080
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Isotype: IgG

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q99JR6
• Gene Symbols: NMNAT3
• Immunogen: Peptide with sequence C-KALGQGQSVKYLLPE.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Form: Liquid