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  5. Tocris Bioscience™ NNC 0640

Tocris Bioscience™ NNC 0640
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Catalog No. 680750
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Catalog No. Quantity
68-075-0 50 mg
68-071-0 10 mg
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Catalog No. 68-075-0 Supplier Tocris Bioscience™ Supplier No. 6807/50
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Description

Negative allosteric modulator of glucagon and GLP-1 receptors

NNC 0640 is a negative allosteric modulator of glucagon receptors (pKi = 7.4). Binds to external surface of the transmembrane domain. Also negative allosteric modulator of glucagon-like peptide 1 (GLP-1) receptor. Inhibits GLP-1-mediated cAMP accumulation in vitro.

Specifications

Chemical Name or Material 4-[[(4-Cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2 H-tetrazol-5-ylbenzamide
CAS 307986-98-7
Quantity 50 mg
Target Glucagon-Like Peptide 1 Receptor Modulators
Molecular Formula C29H31N7O4S
Formula Weight 8737
Purity 98%
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