NO66/C14orf169 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 228421AP150UL

Catalog No. 50-173-3953

Description

Histone demethylase that specifically demethylates ′Lys-4′ (H3K4me) and ′Lys-36′ (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ′Lys-4′ (H3K4me3) and monomethylated H3 ′Lys-4′ (H3K4me1) residues, while it has weaker activity for dimethylated H3 ′Lys-36′ (H3K36me2). Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation. May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.

Specifications

• Antigen: NO66/C14orf169
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RIOX1
• Gene Alias: C14orf169, hsNO66, MAPJD, NO66, Nucleolar protein 66
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79697
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.21 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9H6W3
• Gene Symbols: RIOX1
• Immunogen: NO66/C14orf169 Fusion Protein Ag18721
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG