NO66/C14orf169 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 228421AP
DescriptionHistone demethylase that specifically demethylates ft.Lys-4 ft. (H3K4me) and ft.Lys-36 ft. (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ft.Lys-4 ft. (H3K4me3) and monomethylated H3 ft.Lys-4 ft. (H3K4me1) residues, while it has weaker activity for dimethylated H3 ft.Lys-36 ft. (H3K36me2). Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation. May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|C14orf169, hsNO66, MAPJD, NO66, Nucleolar protein 66|
|Immunoprecipitation, Western Blot|
|NO66/C14orf169 Fusion Protein Ag18721|
|Antigen Affinity Chromatography|
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok