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NO66/C14orf169 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 228421AP

Catalog No. 50-173-3953


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Description

Description

Histone demethylase that specifically demethylates  ft.Lys-4 ft. (H3K4me) and  ft.Lys-36 ft. (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3  ft.Lys-4 ft. (H3K4me3) and monomethylated H3  ft.Lys-4 ft. (H3K4me1) residues, while it has weaker activity for dimethylated H3  ft.Lys-36 ft. (H3K36me2). Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation. May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.
Specifications

Specifications

NO66/C14orf169
0.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9H6W3
C14orf169, hsNO66, MAPJD, NO66, Nucleolar protein 66
Rabbit
IgG
150 μL
-20°C
Primary
79697
Immunoprecipitation, Western Blot
Unconjugated
RIOX1
Liquid
RIOX1
NO66/C14orf169 Fusion Protein Ag18721
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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