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NO66 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A303199AT

Encompass_Preferred

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Catalog No. 50-156-4521


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt.

Histone demethylase that specifically demethylates ′Lys-4′ (H3K4me) and ′Lys-36′ (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ′Lys-4′ (H3K4me3) and monomethylated H3 ′Lys-4′ (H3K4me1) residues, while it has weaker activity for dimethylated H3 ′Lys-36′ (H3K36me2). Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation. May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.
Specifications

Specifications

NO66
Polyclonal
TBS with 0.1% BSA and 0.09% sodium azide
Q9H6W3
RIOX1
Between 50 and 100
20 μL
Primary
Human
Antibody
IgG
Western Blot
Unconjugated
RIOX1
C14orf169; NO66; chromosome 14 open reading frame 169; FLJ21802; MAPJD
Rabbit
Antigen affinity chromatography
RUO
79697
4° C
Liquid
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