Invitrogen™ NOB1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531785

Catalog No. PIPA531785

Description

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (88%), Rat (88%), Rhesus Monkey (97%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA.

Specifications

• Antigen: NOB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nob1
• Gene Alias: 1700021I09Rik; 20S-pre-rRNA D-site endonuclease NOB1; adenocarcinoma antigen recognized by T lymphocytes 4; ART4; ART-4; MST158; MSTP158; nin one binding protein; NIN1/PSMD8 binding protein 1 homolog; NIN1/RPN12 binding protein 1 homolog; NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); NIN1-binding protein; Nob1; Nob1p; phosphorylation regulatory protein HP-10; Pre-rRNA-processing endonuclease NOB1; Protein ART-4; PSMD8 binding protein 1; PSMD8BP1; RNA-binding protein NOB1; rRNA-binding endoribonuclease; YOR056C; YOR29-07
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28987
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.01 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9ULX3
• Gene Symbols: Nob1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 193 of Human NOB1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG