Invitrogen™ NOB1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110036

Catalog No. PIPA5110036

Description

Immunogen sequence: MAPVEHVVAD AGAFLRHAAL QDIGKNIYTI REVVTEIRDK ATRRRLAVLP YELRFKEPLP EYVRLVTEFS KKTGDYPSLS ATDIQVLALT YQLEAEFVGV SHLKQEPQKV KVSSSIQHPE TPLHISGFHL PYKPKPPQET EKGHSACEPE NLEFSSFMFW RNPLPNIDHE LQELLIDRGE DVPSEEEEEE ENGFEDRKDD SDDDGGGWIT PSNIKQIQQE LEQCDVPEDV.

In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA.

Specifications

• Antigen: NOB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nob1
• Gene Alias: 1700021I09Rik; 20S-pre-rRNA D-site endonuclease NOB1; adenocarcinoma antigen recognized by T lymphocytes 4; ART4; ART-4; MST158; MSTP158; nin one binding protein; NIN1/PSMD8 binding protein 1 homolog; NIN1/RPN12 binding protein 1 homolog; NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); NIN1-binding protein; Nob1; Nob1p; phosphorylation regulatory protein HP-10; Pre-rRNA-processing endonuclease NOB1; Protein ART-4; PSMD8 binding protein 1; PSMD8BP1; RNA-binding protein NOB1; rRNA-binding endoribonuclease; YOR056C; YOR29-07
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28987, 291996, 67619
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.17 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q6VEU1, Q8BW10, Q9ULX3
• Gene Symbols: Nob1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human NOB1 (NP_054781.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG