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Invitrogen™ NOC3L Polyclonal Antibody
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Catalog No. PIPA5101731
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PIPA5101731 100 μL
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Catalog No. PIPA5101731 Supplier Invitrogen™ Supplier No. PA5101731
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NOC3L.

GADD 153, a growth arrest and DNA damage-inducible gene, encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10 or C/EBP zeta). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase during cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from classical C/EBP binding sites, recognizing instead unique nonclassical sites. Thus, GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells. GADD 153 belongs to the CBF/MAK21 family, which also includes NOC2L, NOC3L and NOC4L. NOC3L, also designated factor for adipocyte differentiation 24 or Fad24, promotes adipogenesis by controlling DNA replication during the early stages of mitotic clonal expansion (MCE).
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOC3L
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NOC3L
Gene Accession No. Q8VI84, Q8WTT2
Gene Alias AD24; AF233884; C10orf117; factor for adipocyte differentiation 24; Fad24; NOC3 like DNA replication regulator; NOC3 protein homolog; NOC3L; NOC3L DNA replication regulator; NOC3-like DNA replication regulator; NOC3-like protein; nucleolar complex associated 3 homolog; nucleolar complex associated 3 homolog (S. cerevisiae); nucleolar complex protein 3 homolog; Nucleolar complex-associated protein 3-like protein; RGD1560656
Gene Symbols NOC3L
Host Species Rabbit
Immunogen A synthesized peptide derived from human NOC3L(Accession Q8WTT2), corresponding to amino acid residues Y414-W464.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57753, 64318
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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