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Nociceptin receptor Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS0181R

Encompass_Preferred

Catalog No. 50-198-0120


May include imposed supplier surcharges.
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Description

Description

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. The nociceptin receptor is a G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
Specifications

Specifications

Nociceptin receptor
Polyclonal
Unconjugated
Oprl1
K3 opiate receptor; kappa3-related opioid receptor; Kappa-type 3 opioid receptor; KOR3; KOR-3; LC132; LC132 Receptor-Like; morc; MOR-C; N/OFQ receptor; Nociceptin receptor; nociceptin receptor ORL1; nociceptin/ orphaninFQ receptor; nociceptin/orphanin FQ receptor; NOCIR; NOP; NOPr; OFQR; Oor; opiate receptor-like 1; opioid receptor-like 1; opioid receptor-like protein Zf-orl; opioid related nociceptin receptor 1; opioid-receptor-like protein; OPPRL1; Oprl; OPRL1; ORGC; ORL1; Orphanin FQ receptor; orphanin FQ receptor-a; orphanin FQ receptor-b; orphanin FQ receptor-e; peptide receptor; ROR-C; seven transmembrane G protein-coupled receptor; XOR; XOR1
Rabbit
Protein A
RUO
4987
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
P41146
Oprl1
KLH conjugated synthetic peptide derived from mouse Nociceptin receptor .
100 μL
Primary
Human
Antibody
IgG
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