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Nociceptin receptor Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody
Supplier: Bioss BS0181R

Description
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. The nociceptin receptor is a G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.Specifications
Nociceptin receptor | |
Polyclonal | |
Unconjugated | |
Oprl1 | |
K3 opiate receptor; kappa3-related opioid receptor; Kappa-type 3 opioid receptor; KOR3; KOR-3; LC132; LC132 Receptor-Like; morc; MOR-C; N/OFQ receptor; Nociceptin receptor; nociceptin receptor ORL1; nociceptin/ orphaninFQ receptor; nociceptin/orphanin FQ receptor; NOCIR; NOP; NOPr; OFQR; Oor; opiate receptor-like 1; opioid receptor-like 1; opioid receptor-like protein Zf-orl; opioid related nociceptin receptor 1; opioid-receptor-like protein; OPPRL1; Oprl; OPRL1; ORGC; ORL1; Orphanin FQ receptor; orphanin FQ receptor-a; orphanin FQ receptor-b; orphanin FQ receptor-e; peptide receptor; ROR-C; seven transmembrane G protein-coupled receptor; XOR; XOR1 | |
Rabbit | |
Protein A | |
RUO | |
4987 | |
-20°C | |
Liquid |
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
1 μg/mL | |
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH | |
P41146 | |
Oprl1 | |
KLH conjugated synthetic peptide derived from mouse Nociceptin receptor . | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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