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Invitrogen™ NOD1 Polyclonal Antibody
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Catalog No. 01676643
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100 μL
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Catalog No. Quantity
01-676-643 100 μL
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Catalog No. 01-676-643 Supplier Invitrogen™ Supplier No. PA141036
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Description

Rabbit Polyclonal Antibody

Suggested positive control: antigen standard for NOD1 (transient overexpression lysate), recombinant fusion protein. Predicted to cross react with New World Monkey and Mouse.

NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-kappa-B. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOD1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with 50% glycerol and 0.025% sodium azide
Gene NOD1
Gene Accession No. Q8BHB0, Q9Y239
Gene Alias C230079P11; Card4; caspase recruitment domain 4; caspase recruitment domain family, member 4; caspase recruitment domain-containing protein 4; CLR7.1; F830007N14Rik; NLR family, CARD domain containing 1; Nlrc1; Nod1; nucleotide binding oligomerization domain containing 1; nucleotide-binding oligomerization domain containing 1; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1; nucleotide-binding oligomerization domain-containing protein 1; RGD1562269
Gene Symbols NOD1
Host Species Rabbit
Immunogen Amino acids 930-949 of human NOD1 protein.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10392, 107607
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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