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Invitrogen™ NOD1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA141036
Description
Suggested positive control: antigen standard for NOD1 (transient overexpression lysate), recombinant fusion protein.
NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-kappa-B. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.
Specifications
NOD1 | |
Polyclonal | |
Unconjugated | |
NOD1 | |
C230079P11; Card4; caspase recruitment domain 4; caspase recruitment domain family, member 4; caspase recruitment domain-containing protein 4; CLR7.1; F830007N14Rik; NLR family, CARD domain containing 1; Nlrc1; Nod1; nucleotide binding oligomerization domain containing 1; nucleotide-binding oligomerization domain containing 1; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1; nucleotide-binding oligomerization domain-containing protein 1; RGD1562269 | |
Rabbit | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Immunohistochemistry (Paraffin), Western Blot | |
Conc. Not Determined | |
Whole serum with 50% glycerol and 0.025% sodium azide | |
Q8BHB0, Q9Y239 | |
NOD1 | |
Synthetic peptide corresponding to resiudes930-949 of humanNod1 protein. | |
RUO | |
10392, 107607 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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