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Invitrogen™ NOD2 Polyclonal Antibody
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Catalog No. PIPA5104317
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100 μL
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PIPA5104317 100 μL
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Catalog No. PIPA5104317 Supplier Invitrogen™ Supplier No. PA5104317
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NOD2.

NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOD2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NOD2
Gene Accession No. Q8K3Z0, Q9HC29
Gene Alias ACUG; BLAU; CARD15; caspase recruitment domain family, member 15; caspase recruitment domain protein 15; caspase recruitment domain-containing protein 15; CD; CLR16.3; F830032C23Rik; IBD1; Inflammatory bowel disease protein 1; NLR family, CARD domain containing 2; Nlrc2; NOD 2; NOD2; NOD-2; NOD2 protein; NOD2B; NOD-like receptor C2; nucleotide binding oligomerization domain containing 2; nucleotide-binding oligomerization domain 2; nucleotide-binding oligomerization domain containing 2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2; nucleotide-binding oligomerization domain-containing protein 2; PSORAS1
Gene Symbols NOD2
Host Species Rabbit
Immunogen A synthesized peptide derived from human NOD2(Accession Q9HC29), corresponding to amino acid residues A110-G160.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 257632, 291912, 64127
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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