Invitrogen™ Noggin Monoclonal Antibody (A9)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA541655	Invitrogen™ MA541655	200 μL
PIMA543715	Invitrogen™ MA543715	20 μL

Description

Noggin Monoclonal Antibody for Western Blot, IHC (P)

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Specifications

• Antigen: Noggin
• Concentration: 1 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q13253
• Gene ID (Entrez): 9241
• Immunogen: Recombinant protein Noggin. The antigen corresponds to amino acid range 28-232 of the target protein.
• Product Type: Antibody

• Clone: A9
• Content And Storage: -20°C
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG2b κ
• Target Species: Human
• Gene: NOG
• Gene Alias: NOG; Noggin; Noggin precursor; noggin; LOW QUALITY PROTEIN: noggin; SYM1; symphalangism 1 (proximal); SYNS1; SYNS1A
• Gene Symbols: NOG
• Primary or Secondary: Primary
• Purification Method: Protein A/G