Noggin Mouse anti-Human, Clone: OTI1C1, liquid, TrueMAB™

Catalog No.	Quantity
50-167-1406	100 μL

Catalog No. 50-167-1406 Supplier OriGene Supplier No. TA500116

Description

Mouse Monoclonal Antibody

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Specifications

• Antigen: Noggin
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI1C1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: NOG
• Gene Accession No.: Q13253
• Gene Alias: SYM1, SYNS1, SYNS1A
• Gene Symbols: NOG
• Host Species: Mouse
• Immunogen: Recombit protein expressed in E.coli corresponding to amino acids 28-232 of human noggin
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9241
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b