Noggin Mouse anti-Human, Clone: OTI1H8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF500029

Catalog No. 50-165-9304

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Specifications

• Antigen: Noggin
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: NOG
• Gene Alias: SYM1, SYNS1, SYNS1A
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9241
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1H8
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q13253
• Gene Symbols: NOG
• Immunogen: Human recombit protein fragment corresponding to amino acids 28-232 of human noggin produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b