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Invitrogen™ Noggin Polyclonal Antibody
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Catalog No. PIPA522829
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100 μg
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Catalog No. Quantity
PIPA522829 100 μg
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Catalog No. PIPA522829 Supplier Invitrogen™ Supplier No. PA522829
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Description

Rabbit Polyclonal Antibody

Suggested positive control: antigen standard for NOG (transient overexpression lysate). Immunogen sequence: PVLYAWNDLG SRFWP.

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Noggin
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene NOG
Gene Accession No. P97466, Q13253, Q62809
Gene Alias NOG; Noggin; Noggin precursor; noggin; LOW QUALITY PROTEIN: noggin; SYM1; symphalangism 1 (proximal); SYNS1; SYNS1A
Gene Symbols NOG
Host Species Rabbit
Immunogen Synthetic peptide comprising residues 156-170 of the human Noggin protein.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18121, 25495, 9241
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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