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Noggin Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985056
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50-198-5056 100 μL
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Catalog No. 50-198-5056 Supplier Bioss Supplier No. BS2975R
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Rabbit Polyclonal Antibody

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Specifications

Antigen Noggin
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NOG
Gene Accession No. Q13253
Gene Alias Nog; Noggin; Noggin precursor; SYM1; symphalangism 1 (proximal); SYNS1; SYNS1A
Gene Symbols NOG
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Noggin.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9241
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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