Invitrogen™ Nogo Receptor Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518380

Catalog No. PIPA518380

Description

This antibody is predicted to react with canine, mouse, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.

Specifications

• Antigen: Nogo Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RTN4R
• Gene Alias: HGNC:1860; NgR; Ngr1; nogo 66 receptor; Nogo receptor; nogo receptor; Nogo-66 receptor; Nogo66 receptor; nogo-66 receptor; Nogo66 receptor-1; Nogor; OTTHUMP00000197866; reticulon 4 receptor; reticulon-4 receptor; Rtn4r; UNQ330/PRO526
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 113912, 65078, 65079
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q99M75, Q99PI8, Q9BZR6
• Gene Symbols: RTN4R
• Immunogen: Synthetic peptide sequence (LQALPDDTFRDLGN) corresponding to the internal amino acids of RTN4R (aa 166-179).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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