Invitrogen™ Nogo Receptor Recombinant Rabbit Monoclonal Antibody (M5)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547935

Catalog No. PIMA547935

Description

Specificity: The antibody binds to human and rat NgR1 with a Kd of 2.9 nM for both species (bivalent binding).

NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.

Specifications

• Antigen: Nogo Receptor
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: Q99M75, Q99PI8, Q9BZR6
• Gene Symbols: RTN4R
• Immunogen: (His)6-tagged fragment of rat NgR1 (amino acids 278-473).
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG κ

• Applications: ELISA, Flow Cytometry, Immunoprecipitation, Western Blot
• Clone: M5
• Conjugate: Unconjugated
• Gene: RTN4R
• Gene Alias: HGNC:1860; NgR; Ngr1; nogo 66 receptor; Nogo receptor; nogo receptor; Nogo-66 receptor; Nogo66 receptor; nogo-66 receptor; Nogo66 receptor-1; Nogor; OTTHUMP00000197866; reticulon 4 receptor; reticulon-4 receptor; Rtn4r; UNQ330/PRO526
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 113912, 65078, 65079
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid