Invitrogen™ NOMO2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595819

Catalog No. PIPA595819

Description

Immunogen sequence: YALAGVSFEI KAEDDQPLPG VLLSLSGGLF RSNLLTQDNG ILTFSNLSPG QYYFKPMMKE FRFEPSSQMI EVQEGQNLKI TITGYRTAYS CYGTVSSLNG EPEQGVAMEA VGQNDCSIYG EDTVTDEEGK FRLRGLLPGC VYHVQLKAEG NDHIERALPH HRVIEVGNND IDDVNIIVFR QINQFDLSGN VITSSEYLPT LWVKLYKSEN LDNPIQTVSL GQSLFFHFPP LLRDGENYVV LLDSTLPRSQ YDYILPQVSF TAVGYHKHIT LIFNPTRKLP EQDIAQGSYI ALPLTLLVLL AGYNHDKLIP LLLQLTSRLQ GVGALGQAAS DNSGPEDAKR QAKKQKTRRT; Positive Samples: BxPC3; Cellular Location: Endoplasmic reticulum membrane, Single-pass membrane protein.

This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). Two transcripts encoding different isoforms have been described.

Specifications

• Antigen: NOMO2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NOMO2
• Gene Alias: nodal modulator 2; Nomo; NOMO2; PM5; pM5 protein 2; pM5 protein, centromeric copy
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 283820
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.97 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q5JPE7
• Gene Symbols: NOMO2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 873-1222 of human NOMO2 (NP_0010040601).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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