Norepinephrine Transporter Mouse anti-Human, Mouse, Rat, Clone: CL3063, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524647
Immunogen sequence: SLYYLFSSFT LNLPWTDCGH TWNSPNCTDP KLLNGSVLGN HTKYSKYKFT PAAEFYERGV LHLHESSGIH DI Binds to an epitope located within the peptide sequence HTKYSKYKFTPAAEF as determined by overlapping synthetic peptides.Norepinephrine Transporter [NET, or noradrenaline transporter (NAT)] is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression. Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD.
|PBS with 40% glycerol and 0.02% sodium azide; pH 7.2|
|Sodium-dependent noradrenaline transporter, NET, Solute carrier family 6 member 2, SLC6A2, NAT1, NET1, SLC6A5|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|20538, 6530, 83511|
|Recombit protein corresponding to Human Norepinephrine Transporter|
|Human, Mouse, Rat|
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