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NOSIP Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735797 Shop All Proteintech Group Inc Products
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50-173-5797 150 μL
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Catalog No. 50-173-5797 Supplier Proteintech Group Inc Supplier No. 279791AP150UL
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Description

Rabbit Polyclonal Antibody

NEDD4L is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. NEDD4L promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. NEDD4L also promotes ubiquitination and degradation of SGK.

Specifications

Antigen NOSIP
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene NOSIP
Gene Accession No. Q9Y314
Gene Alias CGI 25, eNOS interacting protein, NOSIP
Gene Symbols NOSIP
Host Species Rabbit
Immunogen NOSIP Fusion Protein Ag27569
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51070
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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