Invitrogen™ NOTCH1 Recombinant Rabbit Monoclonal Antibody (7L3V4)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535256

Catalog No. PIMA535256

Description

Immunogen sequence: ILPQESPALP TSLPSSLVPP VTAAQFLTPP SQHSYSSPVD NTPSHQLQVP EHPFLTPSPE SPDQWSSSSP HSNVSDWSEG VSSPPTSMQS QIARIPEAFK.

The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures. The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1. Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).

Specifications

• Antigen: NOTCH1
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P46531, Q01705
• Gene Symbols: Notch1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 2456-2555 of human Notch1 (P46531).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunoprecipitation, Western Blot
• Clone: 7L3V4
• Conjugate: Unconjugated
• Gene: Notch1
• Gene Alias: 9930111A19Rik; AOS5; AOVD1; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; notch receptor 1; Notch1; p300; RP23-306D20.12; RP23-306D20.12-001; Tan1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18128, 4851
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid