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Notch1 Mouse anti-Human, Clone: OTI3E12, liquid, TrueMAB™
SDP

Catalog No. 501671389
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50-167-1389 30 μL
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Catalog No. 50-167-1389 Supplier OriGene Supplier No. TA500078S
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Description

Mouse Monoclonal Antibody

The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures. The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1. Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).

Specifications

Antigen Notch1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3E12
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene NOTCH1
Gene Accession No. P46531
Gene Alias AOS5, AOVD1, TAN1, hN1
Gene Symbols NOTCH1
Host Species Mouse
Immunogen Recombit protein expressed in E.coli corresponding to amino acids 2300-2556 of human NOTCH1
Purification Method Affinity Chromatography
Quantity 30 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4851
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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