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Notch1 Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™
SDP

Catalog No. 501993768
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50-199-3768 10 μg
50-199-3767 100 μg
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Catalog No. 50-199-3768 Supplier Active Motif Supplier No. 91244
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Description

Mouse Recombinant Monoclonal Antibody

The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures. The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1. Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).

Specifications

Antigen Notch1
Applications Western Blot
Classification Monoclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Notch1
Gene Accession No. P46531
Gene Alias 9930111A19Rik; AOS5; AOVD1; BOS_12152; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; Neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; Notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; NOTCH1; p300; RP23-306D20.12; RP23-306D20.12-001; TAN1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1
Gene Symbols Notch1
Host Species Mouse
Immunogen This antibody was raised against a recombinant protein corresponding to the intracellular domain of human Notch1.
Purification Method Protein A
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4851
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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