Invitrogen™ NOTCH4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540479

Catalog No. PIPA540479

Description

Peptide sequence: KALKPKAEVD EDGVVMCSGP EEGEEVGQAE ETGPPSTCQL WSLSGGCGAL Sequence homology: Cow: 92%; Dog: 77%; Guinea Pig: 79%; Horse: 92%; Human: 100%; Pig: 100%; Rabbit: 79%.

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).

Specifications

• Antigen: NOTCH4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NOTCH4
• Gene Alias: DAQB-143M3.4; FLJ16302; hNotch4; Int3; Int-3; MGC74442; N4; neurogenic locus notch homolog protein 4; Notch 4; Notch 4 extracellular truncation; Notch 4 intracellular domain; Notch gene homolog 4; Notch homolog 4; notch receptor 4; NOTCH3; Notch4; putative Notch4 protein; Transforming protein Int-3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4855
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q99466
• Gene Symbols: NOTCH4
• Immunogen: Synthetic peptide directed towards the middle region of human NOTCH4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov